The results of investigation of reaction-diffusion type models demonstrating diffusion instability are presented. In particular, in general case the condition for both Turing and wave instabilities are obtained for three equations of this type with the diagonal diffusion matrix. Qualitative properties of the system, in which bifurcations of each of the two types can take place, are clarified. Investigation of a set of amplitude equations, describing interaction of several modes which became unstable due to the wave bifurcation, is carried out.